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What is AMH (Anti-Müllerian Hormone) & Why Does it Matter?

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What is AMH (Anti-Müllerian Hormone)?

  AMH stands for anti-mullerian hormone. This is a hormone that is made in the ovary (specifically by cells called granulosa cells, which function to nourish and support a women’s eggs). When a woman has more eggs within their ovaries, there will be more granulosa cells producing more of the AMH hormone.   Anti-Müllerian Hormone Test

Why are they important to fertility?

  There is no absolute way to measure egg number in females. Instead as fertility specialists, we assume egg number or what is called an ovarian reserve. AMH is one of the measures of ovarian reserve. When the AMH is low, this is concerning for diminished ovarian reserve (or a decline in egg number). When the AMH is high this may predict a higher than average egg number, or it can be associated with another condition called polycystic ovary syndrome (PCOS).   amh levels important to fertility   There are age-related averages for AMH that help women understand if they are above average for their age, the average for their age or below average for their age. Additionally, AMH values are important infertility treatments for women. They help determine the dosing of certain hormone medications for either an IVF cycle done for infertility or the dosing of hormones for women who are completing an egg freezing cycle. Since ovarian follicles generate anti-müllerian hormone in adulthood, calculating the rates of anti-müllerian hormone in blood offers a solution to estimate ovarian reserve in women. For this reason, anti-Müllerian hormone levels are routinely used to figure out how well a female will react to ovarian stimulation for in vitro fertilization fertility treatment, as well as what doses of hormones really should be used during IVF.

Do you recommend women get their AMH levels tested? Is this typically covered by insurance?

    AMH Fertility Test If you have ever thought about your fertility or egg numbers, then it’s a good idea to get your AMH test levels checked. It’s a simple blood test that can be ordered by your physician and it is often covered by insurance plans. Knowing your AMH can help you be proactive and make the appropriate choices for your future. For example, if you are not currently planning to start a family, and you test your AMH and it is lower than average for your age, it could prompt you to consider egg freezing or embryo freezing. The important thing to remember that any single blood test (Anti-Müllerian Hormone Test) only assesses the status at this moment in time. It does NOT predict the future. All women have a decline in ovarian reserve and egg number year after year and therefore, having a high AMH now does not mean that your AMH will remain high in 2 years.

What questions should women ask their doctors about AMH levels? Explain.

  Depending on your fertility goals, ask your doctor if it is worthwhile to have your AMH levels tested. There are some other measures of ovarian reserve that can also be considered, such as a cycle day 2 or 3 FSH and estradiol level (blood tests) or a pelvic ultrasound to assess your antral follicle count.

Anything else to add?

  There are good studies that indicate that AMH does not predict your ability to have a child. For example, if your AMH is low for your age, this does NOT mean that you cannot get pregnant or have infertility. It is just a measure of your ovarian reserve based on averages.  fertility questions to ask orange county ivf clinic

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