Fulfill Your Dreams of Parenthood
We believe each and every patient is unique so our approach to patient care is to make the fertility experience easier and less stressful. At Eden Centers for Advanced Fertility, we have a highly skilled team of Physicians and staff who focus on patient care. We will help you fulfill your dream of building a family.
IVF treatment process can help infertile couples overcome their fertility issues and help patients achieve pregnancy. At IVF fertility clinic in Orange County, you will receive personalized attention based on your individual conditions and indications. Our team of clinical IVF specialists, reproductive endocrinologists, board certified fertility doctors, nurses, and embryologists work together under the same roof to create an IVF treatment and diagnosis plan to help our patients achieve pregnancy.
What is IVF?
By definition, artificial insemination deposits sperm in a woman’s uterus. The term “test tube babies” is a synonym for IVF. Before you decide to follow the treatment and go for an IVF clinic in orange county, we suggest that you learn as much as possible about IVF. By being well informed about everything involved in the procedure, you will have more peace of mind when you start your IVF treatment in Orange County.
In Vitro Fertilization (IVF) is one of the types of Assisted Reproductive Technology (ART) in which sperm and eggs are combined outside the body, in the lab. IVF is a modern technology which has been in use for over three decades, and has led to the birth of over 8 million children. Its is most widely used ART procedure. IVF treatment is often used when a woman’s fallopian tubes are blocked or when a man has a low sperm count.
Once the egg is fertilized, cell division is initiated, resulting in an embryo which can be transferred into the uterus of the woman. The embryo can then implant in the uterine lining (endometrium) and further develops into a pregnancy.
Since the fertilization happens outside of the uterus, IVF can be done with the help of a partner’s sperm and the woman’s eggs or eggs or sperm from a known or anonymous donor. Additionally, the pregnancy can be carried by a gestational carrier/surrogate.
In addition to In-Vitro Fertilization, there are other types of ART. These techniques may be combined with IVF to increase the likelihood of a successful pregnancy or decrease risks of some disorders.
These technologies comprise of –
The specialized technique of Intracytoplasmic Sperm Injection proves beneficial in fertilizing the egg where the sperm cannot enter the outer layer. During this technique, the cytoplasm of the egg is injected with a single sperm.
The embryologist selects the best appearing sperm cell to use for fertilization of each egg. ICIS increases the chances of fertilization in some citations. Additionally, during the ICSI procedure the embryologist will learn useful information about the quality of the eggs and sperm.
Preimplantation Genetic Screening (PGS) / Preimplantation Genetic Testing for Aneuploidy (PGT-A)
This technique involves DNA analysis of biopsied cells from an embryo, to look for chromosomal errors. This allows the laboratory to select the most viable embryos for implantation. PGT-A can help avoid transferring embryos that have a low or no chance of becoming a healthy pregnancy or those that may lead to a miscarriage.
Chromosome errors increases with advancing female age. This contributes to lower fertility and an increased miscarriage rates among older women. Aneuploidy may also cause unexplained infertility and recurrent miscarriages in some younger women.
PGT-A can also reveal the genetic sex of each embryo (46 X for female or 46XY for male). Therefore, PGT-A can also be utilized during IVF for sex/gender selection and family balancing.
Preimplantation Genetic Diagnosis (PGD)
In addition to testing for chromosome errors, the cells biopsied from an embryo can be analyzed for various single gene mutations or familial hereditary conditions. Preimplantation Genetic Diagnosis may be recommended for couples who are carriers of a genetic disorder, which may lead to disability or disease in their offspring, such as muscular dystrophy or cystic fibrosis.
PGD is able to identify both unaffected and carrier embryos By identifying unaffected non-carrier embryos PGD can allow a family to eliminate the risk of transmitting a particular mutation to future generations.
Egg, Sperm and Embryo Freezing
Cryopreservation of eggs, sperm, and embryos allows the individual or couple to pursue their fertility at a later date. A frozen embryo can be thawed and transferred into the uterine cavity, which is first prepared with hormones or by optimal timing in a natural menstrual cycle.
Frozen embryo transfer (FET) can produce high success rates and allows patients to conceive at a convenient time. Once frozen, the eggs, embryos, and sperm, they can remain that way for years, without loss of quality.
Can IVF Help Me?
Comprehensive knowledge of IVF technologies can prove beneficial for the individuals and couples who wish to grow their families.
The following are some of the main conditions where both IVF and other ARTs can be employed –
Female Infertility –
The best candidates for IVF treatment are women with damaged fallopian tubes. Since IVF lets the fertilization to take place outside the fallopian tubes, it assists women to achieve pregnancy when facing the following conditions –
- Tubal sterilization, or tubal removal
- Anovulation / Polycystic ovary syndrome (PCOS)
- Fallopian tube damage
- Unexplained infertility
- Age-related infertility and Diminished Ovarian Reserve (DOR)
IVF can be helpful for male patients who have impaired sperm function or production. There are many causes for male infertility including defects sperm production and transport due to infections, spinal cord injury, tumors, injuries, and other medical and genetic conditions. Often the cause of male infertility is uncertain. IVF with ICSI and in some cases testicular sperm extraction (TESE or PESA) can be utilized to create embryos and achieve a pregnancy.
Recurrent Pregnancy Loss (RPL)
RPL is defined by two or more clinical pregnancy losses. There are many factors which can contribute to RPL the most common are aneuploidy of eggs/embryos, uterine factors due to infection or structural abnormalities including fibroids and uterine septum, hormonal abnormalities including thyroid disorders and diabetes, autoimmune disorders, infections, and other medical and genetic issues. Some causes of RPL can be overcome with IVF treatment in Orange County, while others require surgical or medical treatment.
Heredity Genetic Conditions
Couples may be able to achieve pregnancy spontaneously, but may have concerns about a particular genetic condition that affects their family. IVF can be combined with PGD to rule out transmission of specific hereditary genetic conditions but only transferring unaffected embryos. The following are some genetic disorders which can be tested for –
- Sickle cell disease
- Tay-Sachs disease
- Spinal muscular atrophy (SMA)
- Cancer gene mutation (BRCA1 or BRCA2)
- Duchenne muscular dystrophy
- Cystic fibrosis
- Fragile X syndrome
Egg, sperm and embryo freeze for future use is increasingly common. These procedures help women and men to preserve their fertility until they are ready to start or grow their family. Many single women opt to freeze eggs while they are at peak fertility until they are ready to start a family, thereby circumventing some of the adverse effects of reproductive aging. People working under high-risk conditions such as – industrial work, military, or chemistry may opt for fertility preservation to mitigate risk of unexpected loss of fertility loss.
Today, the medical field has made immense progress; this has led to a significant rise in cancer survival rates, especially for prostate cancer breast cancer, lymphoma and leukemia. Radiation and chemotherapy can harm the reproductive systems of both the male and female cancer patients.
Women with cancer may opt to harvest and freeze eggs before starting cancer treatment. Eggs can be fertilized using the sperm of a partner or donor via IVF to freeze embryos. Male patients may opt to freeze sperm or testicular tissue before cancer treatment.
LGBTQIA Family Building
Using reproductive medicine, today, it is feasible for LGBTQIA community to enjoy parenthood. Third party reproductive options including the use of donor gametes and gestational carriers has expanded the access and safety of building options for the LGBTQIA community. A tolerant legal framework in California has enabled protections to families and their children often lacking elsewhere in the world.
Donor sperm intrauterine insemination (IUI) is an established option for pregnancy in single and lesbian women. Donor sperm can be obtained from either an anonymous or directed donor. allows both women to contribute to the pregnancy couples. With the help of IVF, eggs from one partner can be fertilized along with donor sperm, and the resulting embryos are than implanted into the uterus of the other partner.
Gay men can build a family though IVF with the assistance of an egg donor and a gestational carrier.
How Does IVF Work?
IVF involves the following steps –
- Ovarian Stimulation
- Retrieval of Eggs
- Sperm Collection
- Embryo Selection
- Embryo and Transfer
Before proceeding with IVF, the uterus of the patient will be evaluated. This is done to ensure that there are no issues that require surgical repair. For pre-cycling testing, the physicians will –
- Evaluate thyroid function.
- Evaluate the ovarian reserve.
- Evaluate both partners for sexually transmitted infections.
- Investigate the semen of the male partner.
Women take injectable and oral fertility medications to stimulate the ovaries for 7 to- 14 days. Stimulating the ovaries helps multiple eggs to mature, which increases the chances of achieving a pregnancy through IVF.
During stimulation the patient will visit the VF center for brief monitoring visits. At each visit an ultrasound exam is performed to monitor the number, size, and rate of follicle growth. With the help of blood tests, a woman’s hormonal response to the medication is also measured.
When the follicles have grown sufficiently, the trigger shot is given. This injection is given to induce the final egg maturation and triggers ovulation at a specific time.
Retrieval of Eggs
This retrieval process includes a surgical procedure where you are given a mild sedative (twilight anesthesia) through an IVF. Once you are sedated, the physicians will conduct a vaginal ultrasound. A thin needle will be inserted into the ovary through the vaginal wall. The needle will enter each ovarian follicle and with mild suction, the fluid and the egg, that comes with it, will be withdrawn and handed off to the embryologist.
Sperm Retrieval & Collection
Ejaculated semen collected through masturbation is washed and processed to isolate the most viable sperm cells.
If there is no sperm or every poor quality sperm in the ejaculate,the Urologist can surgically retrieve sperm from the testicle(s) by an aspiration or extraction procedure, such as PESA or TESE or PESA. Donor sperm can be used for backup incase on sperm is obtained from the testicles.
IVF can be accomplished by one of two methods. The first method conventional fertilization involves placing thousands of sperm cells with each egg in a culture dish and allowing fertilization to happen on its own. Alternatively, one normal appearing sperm cell is selected by the embryologist and injected with a tiny needle directly into an egg in a technique known as ICSI. The eggs are checked the next day to see how many of them are normally fertilized.
Normally fertilized eggs are kept in culture to develop into embryos for 2 to 3 days (cleavage stage embryos) or 5 to 6 days (blastocyst stage embryos).
Embryo Selection and Transfer
Your physician may advise PGS/PGT-A (Preimplantation genetic screening) / Preimplantation genetic testing for Aneuploidy), or PGD (preimplantation genetic diagnosis). Embryos undergo a biopsy to remove cells for genetic testing. The DNA of cells removed from the embryo is analyzed by a specialized genetics laboratory.
Embryos with highest pregnancy potential are also selected by their microscopic appearance and rate of development. The embryo transfer, procedure can be performed using either cleavage or blastocyst stage embryos. The embryos can be either fresh or thawed after previously being frozen.
Under ultrasound, guidance a soft (catheter) is passed through the cervix into the uterus. Near the tip of the catheter, in a small drop of fluid containing the embryo(s) is loaded. The physician will then embryo(s) in the optimal position in the uterus.
A Transvaginal ultrasound will help in having a clear view of the embryo(s) placement within the uterine lining, which improves the likelihood of pregnancy.Surplus embryos can be frozen and stored for future pregnancy attempts.
Surplus embryos can be frozen and stored for future pregnancy attempts.
After the Transfer
Once the embryo is transferred, the patient is advised to limit her activities for several days. The patient is guided about the “do’s and don’ts” during this time. In case a fresh embryo is transferred, the ovaries may still be enlarged, and additional limitations may be recommended to minimize risks of ovarian hyperstimulation syndrome and other complications.
One cycle of IVF is usually 2-3 weeks from the time of initiating injectable medications to the time of egg retrieval. In some patients more than one cycle is advised to obtain enough eggs and embryos to maximize pregnancy chances.
The decision of whether to proceed with a fresh embryo transfer or to cryopreserve all embryos and have a subsequent frozen embryos transfer is individualized. Pregnancy rates and risk or ovarian hyperstimulation syndrome, as well as, implications for fetal development, placental implantation, and infant outcomes should be weighed in this decision.
IVF by The Numbers
- 8 Million + Number of babies born across the world, through IVF Treatment
- 12 % – Percent of reproductive age women who experience impaired fertility.
- 2% – This is the percentage of all the infants born in the United States of America, every year, that are conceived by IVF.
Eden offers IVF treatment services in Orange County California and its surrounding areas, while providing quality patient care. Our IVF specialists have helped many infertile couples overcome their fertility issues and provided them with a chance to conceive and bear children. Check out Our full range of fertility treatments here.
Also check out our growing library of videos & articles to better understand fertility. We also organize free fertility seminars for our potential patients, these seminars are organized by qualified doctors in our IVF centers located in Newport Beach & Fullerton.